Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOB preferentially degrades benzylamine and phenylethylamine.
[1] Human monoamine oxidase A and B genes exhibit identical exon-intron organization.Grimsby J., Chen K., Wang L.J., Lan N.C., Shih J.C.Proc. Natl. Acad. Sci. U.S.A. 88:3637-3641(1991) [2] cDNA cloning of human liver monoamine oxidase A and B: molecular